Anti-Ageing Theory By Omorfee

Anti-Ageing Theory

Looking and feeling young has never been so easy! Here are few theories explained which defines aging theories and why we age-

 1)    THE THYMIC THEORY OF AGING

The thymus is a gland needed for normal immune function It secretes hormones called humoral factors. These hormones help to develop the immune system. The thymus is responsible for the production of T-lymphocytes (T cells), which are critical cells of the immune system. Thyme hormones may also play a key role in stimulating and controlling the production of neurotransmitters, and endocrine system hormones, which means they may be key regulators of aging and responsible for immunity.

2)     CALORIE RESTRICTION ANTI-AGING THEORY

Calorie restriction (CR) or energy restriction is a dietary routine wherein there is a reduced intake of calories without causing malnutrition or any other nutritional deficiency. It can improve longevity and health in model organisms. Studies in humans also demonstrate reduced risk factors for major diseases when they are on calorie restriction diet. Calorie restrictions retards several aspects of the aging in mammals, including mortality, tumorigenesis, physiological decline, extend life, and helps delay the onset of disease as well.

3)     PROGRAMMED THEORY OF AGING

Programmed theory asserts that the human body is designed to age and there is a certain biological timeline that our bodies follow. Programmed Longevity: Aging is caused by certain genes switching on and off over time.

4)     CROSS-LINKING THEORY OF AGING

With age, proteins, DNA and other structural molecules develop abnormal bonds or cross-links to one another. These abnormal bonds decrease the mobility or elasticity of proteins. These damaged proteins, accumulate in the cells and create problems. Cross-linking of the skin protein, collagen, has been shown to be responsible for wrinkling and other age-related changes in skin. Cross-linking of proteins in the lens of the eye play a major role in cataract formation. Cross-linking of proteins in the walls of arteries or the filtering systems of the kidney account for at least some of the atherosclerosis (once called hardening of the arteries) and age-related decline in kidney function observed in older adults. 


5)    DNA/RNA DAMAGE

The most of anti-aging theories demonstrate that DNA damage is central in aging processes. Decay of the integrity of chromosomal DNA will cause a loss of function.
DNA damage refers to chemical changes in the structure of DNA molecule, producing structural abnormalities causing dysfunction of DNA. Mutations are changes in the polynucleotide sequence (deleted, substituted, added, and rearranged). Both interfere with gene expression, which is proposed as possible mechanism of aging and much degenerative disease.